Somewhat. It’s moreso that it’s just that it tends to be something like having male chromosomes but something happened to the Y chromosome, so you end up with someone with the body of a woman. In most cases it does not end up with male and female 50/50, at least from my knowledge.
Others may call these combinations a “3rd sex,” I call them a combination of the two sexes, but that’s from personal choice, because you can’t use it as a 3rd sex for reproduction - rather, they tend to have problems with biologically having children, but not always.
Do you mean the binary two genders/male-female system vs. the more than 2 gender system?